| Review: |
This book describes the origins, methods, and results of a large-scale study that systematically addressed why some people are highly vulnerable to psychiatric and substance abuse disorders and others aren’t. It looks at how genes and environment interweave in producing risk. The authors first introduce the statistical methods that they are using, and then go on to look, in detail, at the genetic risk (examining standard twin models applied to a large array of substance abuse users) and the environmental risk (such as parent-child relationships). A range of issues, such as differences in sex and the causes of stability and change in psychopathology, are also discussed. The study addresses a number of questions, including whether risk is disorder-specific, how can one distinguish between correlational and causal genetic and environmental factors, how do sex differences affect risk, and how risk and protective factors interact over time. |