| Review: |
Salmonella infection ranks second amongst causes of food-borne illnesses: every year millions of people worldwide become ill and thousands die as a result of infection from food-borne pathogens. In recent years Salmonella-resistance to antibiotics has become a problem and the development of new drugs that deal with bacterial proliferation without harming the mammalian host cells are being investigated. Another area of research is based on gene manipulation and molecular methods to develop auxotrophs that are attenuated for toxicity and do not cause septic shock. This book presents detailed methods and techniques that have become landmarks in advancing our knowledge of Salmonella. Topics, amongst others, include molecular genotyping, new rapid, accurate, and sensitive determination of antibiotic resistance profiles, and basic research to characterize Salmonella-specific antigens. |