Prostate Cancer. Biology, Genetics and the New Therapeutics
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Author(s): L. Cheung, W. Isaacs and J. Simons (Eds)
Publisher: Humana Press
ISBN: 9781588296962
Format: hardback
508pp
Price: $179.00
Review Date: 25 October 2007
Review: Unlike other books on prostate cancer, this book focuses on the exciting developments in research and their translation from bench to bedside in the areas of: biology and imaging; cancer genetics; and novel therapeutics of human prostate cancer. In this new edition, the first section on biology and imaging has been expanded to include recent developments in the imaging of prostate cancer, such as non-invasive imaging methods to track gene expression in living subjects, the use of quantum dot nanotechnology fro the visualization of localised and disseminated tumours in mice. With the sequencing of the human genome, much progress has also been made in understanding the genetics of human prostate cancer with technological advances in high-throughput sequencing, genomics and bioinformatics. With new therapeutics, new horizons and approaches for potentially curative intervention have emerged. Epidemiology and gene–environment interaction in human prostate cancer are reviewed, with examples focusing on unique features such as racial differences and the contributions of the environment. The book gives a glimpse into the future of prostate cancer research, including much that will be translated into the clinic to improve the diagnosis, prognosis and treatment of this disease.