Acne and its Therapy
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Author(s): G. Webster and A. Rawlings (Eds)
Publisher: Taylor & Francis
ISBN: 9780824729714
Format: hardback
311pp
Price: £115.00
Review Date: 20 July 2007
Review: This, the latest volume in the Basic and Clinical Dermatology series, the 18 chapters review the latest developments in the understanding of acne and its treatment. There are three parts: the biology of the sebaceous gland and pathophysiology of acne; acne treatments; and acne delivery, formulation and testing. The contents cover the molecular and cell biological aspects of sebocytes, sebaceous glands, and the pilosebaceous unit through to the pathogenesis of acne, its treatment with hormones, antimicrobials, retinoids, and laser. Novel activities are reviewed, such as the effect of octadecenedioic acid, sphingolipids and enzyme inhibitors. Formulation principles and the importance of follicular delivery through sebum are described and in vitro testing methods are also covered.