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| AIDS Vaccine Research | Buy a
book...
|
| Author(s): | F. Wong-Staal and R. C. Gallo |
| Publisher: | Marcel Dekker |
| ISBN: | 0824706455 |
| Format: | hardback |
| 343pp | |
| Price: | $165.00 |
| Review Date: | April 29, 2002 |
| Review: | This book provides a state-of-the-art review of the present research into AIDS vaccines. Medical science knows more about this human pathogen than almost any other causative agent, but it still remains without a solution. There has been a debate as to whether a vaccine must be able to prevent HIV infection completely or whether we should be satisfied with a vaccine that prevents the disease but not the infection, which is a more realistic goal. There are chapters on: immunopathogenesis of HIV infection; the genetic diversity of HIV-1; the role of cytotoxic T lymphocytes in protection; the immune reconstitution; the design of engineered vaccines; DNA vaccines; replication-deficient, pseudotyped HIV-1 vectors as vaccines; the development of mucosal DNA vaccines using live attenuated Salmonella typhi as a vaccine delivery system; innate immunity in HIV infection; the role for nonhuman primate models in the development and testing of vaccines; and an international perspective on HIV vaccine development. |