The Complement Facts Book
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Author(s): B. J. Morley and M. J. Walport (Eds)
Publisher: Academic Press
ISBN:  0 1273 3360 6
Format: softback
  228pp
Price: £31.95
Review Date: May 23, 2000
Review: The aim of this manual is to present concise biochemical information about the proteins of the complement system. From it, readers will be able to keep track of basic information on the proteins with which they work and find out details of their physicochemical properties, amino acid sequences and structure. Entries are classified under the following headings: Other names; Physicochemical properties; Structure; Function; Tissue distribution; Regulation of expression; Protein sequence; Protein modules; Chromosomal location; cDNA sequence; Genomic structure; Accession numbers; Deficiency, and Polymorphic variants. It contains entries on all the components of the complement system, including C1q and collectins, C3 family proteins, serine proteases, regulators of compliment activation, cell surface receptors and terminal pathway proteins.